Arecanut (Areca catechu L.) seed polyphenol improves osteoporosis via gut-serotonin mediated Wnt/β-catenin pathway in ovariectomized rats
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منابع مشابه
Transcriptome sequencing and de novo assembly in arecanut, Areca catechu L elucidates the secondary metabolite pathway genes
Areca catechu L. belongs to the Arecaceae family which comprises many economically important palms. The palm is a source of alkaloids and carotenoids. The lack of ample genetic information in public databases has been a constraint for the genetic improvement of arecanut. To gain molecular insight into the palm, high throughput RNA sequencing and de novo assembly of arecanut leaf transcriptome w...
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The title compound isolated from Areca catechu L. (common name: arborinol methyl ether; a member of the arborane family) was established as 3α-methoxyarbor-9(11)-ene, C(31)H(52)O. Rings A/B/C/D assume a chair conformation, while ring E has an envelope conformation. The absolute configuration was determined to be (3R,5R,8S,10S,13R,14S,17S,18S, 21S) by analysis of Bijvoet pairs based on resonant ...
متن کاملAntiosteoporotic effect of icariin in ovariectomized rats is mediated via the Wnt/β-catenin pathway
Icariin (ICA), the main active flavonoid glucoside isolated from Herba Epimedii, has been shown to prevent postmenopausal bone loss in vitro. However, the mechanisms by which ICA prevents bone loss in vivo remain poorly understood. In the present study, the effect of ICA in an ovariectomized (OVX) rat model of osteoporosis was evaluated. Sprague-Dawley rats were divided into sham-operated and O...
متن کاملArecanut, Areca catechu L. as such is not carcinogenic in normal dose if chewed without tobacco: compilation of research work
Review of literature on the health effects of arecanut chewing shows that it is not carcinogenic in normal dose. It was reported that an adult human being masticate up to 0.5g of arecanut/kg bw/day. Animal studies have revealed that feeding of processed arecanut (dried or boiled) at 1.0g/kg body weight/day and pan masala up to 1.67g/kg bw/day were safe for mice. Arecanut paste when applied to b...
متن کاملA Review on Phytochemical and Pharmacological Potential of Areca Catechu L. Seed
Arecanut seed has been used for medicinal properties more than 2000 years in South Asian countries. In fact, various pharmacological activities have been found in the arecanut seed extract or its constituents. Prevention of oxidative stress induced diseases is an urgent problem in all over the world. Traditional use of the plant for medicinal properties is to be documented for their possible us...
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ژورنال
عنوان ژورنال: Journal of Functional Foods
سال: 2021
ISSN: 1756-4646
DOI: 10.1016/j.jff.2021.104598